On August 14, 2025, the U.S. Environmental Protection Agency (EPA) released its latest biannual update to the Toxic Substances Control Act (TSCA) Inventory—a key resource for those working with chemicals in the U.S. market.
The non-confidential portion of the Inventory remains publicly available, while access to substances claimed as Confidential Business Information (CBI) still requires a valid bona fide intent to manufacture or import.
So, what’s new in this update? Here’s a quick breakdown:
- Refreshed non-confidential TSCA Inventory data
- Updates to the TSCA Master Inventory File (includes CBI listings)
- Adjustments to commercial activity status
- Changes to unique identifier data
- Adjustments to regulatory flags (including Significant New Use Rules and test orders)
As of this update, the TSCA Master Inventory includes 86,862 chemicals, with 42,578 of them actively used in U.S. commerce. Additionally, the EPA continues its ongoing review of CBI claims, resulting in some substances being moved into the public (non-confidential) inventory.
When Will the Inventory Be Next Updated?
The next TSCA Inventory update is expected in Winter 2026.
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Published August 15th, 2025
This article was generated with the assistance of Artificial Intelligence.